I'll definitely +1 for Routy's F/C's!! I'm 6'4" with a 36" inseam @230#. The bike went from barely rideable for me, to my daily driver. Minimum 30 miles a day, and so comfortable the bike often demands that I take the long way home. Now, I will say that the set up is not yet perfect. The stock seat is now good for about an hour, maybe a bit more. The next thing I'll do is the lift on the front of the seat. That should help relieve the tailbone pressure. I'm also considering a Harley Police seat mod, or possibly a custom. I sat on a Corbin, and didn't like it because it pushed me about an inch forward, and lowered me about an inch. Both exactly counter to what I need.
I have a CanAm Spyder RT with a $1000.00 custom seat. It has a full 4" lift over stock which is all they could give me. Beautiful work, but it did not fix my problem. I'm simply too long in the leg to fit that bike with the pegs under me. I've determined the problem would be the same on any bike with that peg placement. {Goldwings, BMW's, etc.}That leaves the best option for me being forward control cruiser-type bikes.
In both bikes, moving my feet forward {highway pegs on the Spyder} made the most immediate improvement, and for the least money! I'd also recommend getting your feet where you want them before moving the seat around, other than maybe the seat nose lift. As I understand it that mod is easily reversible/removable.
As an interesting side note, I've had the Spyder about a year, and put about 13,500 miles on it. I bought the S40 because I wanted a simple, inexpensive bike to chase the wife around on when she's on her bike. I started riding the S40 full time a couple of months ago, while I'm working on the Spyder. Now the Spyder sits in the shed, still waiting my attention! As soon as I can I'm going to unload my high tech $25,000 trike, and keep my $5000 thumper. Kinda an expensive way to learn what I really want to ride..