Well let's see...
I bought my 05 used in 07 with 2400 mi. on it.
Took it immediately on a 12,000 mi. trip cross country, and ride it almost all the time!has 25,000 on it now!
I've only changed oil, pads and tires.
Don't let it (or ANY engine) run out of oil. That's pretty much the only way you can kill this thing.
I haven't even checked the cam chain, battery! or valves yet. (don't worry, I will)
It's a MACHINE! Treat it as such, and I'm sure it will act like one!
But it is a really reliable and pretty simple one at that.
Besides tinkering is half the fun. If you don't like that sort of thing there is always someone out there that will do it for you. (For a fee!)
Good rule of thumb is just have it checked and oiled ever 3 months or so, and, whatever comes up comes up! Take care of it and don't let things go.
Run it often!! (Which you said you would, so no problem!)
Any repair cost is not that bad. Comparatively. (read: Harley)
Am I sounding "Mechanically" yet?
I could go on.......
Anyway, what I'm saying is: I love this bike! and, I would do anything for it!
Including fixing it!