When I screw my air/fuel mixture screw all the way in it doesnt make the engine slow down / rough idle, but when I back it out it will eventually hit a point where the engine starts to slow, I’ve been messing with pilot, main jet and spacers, is that normal for the mixture screw to do nothing when screwed all the way in?

I went up one size on both main and pilot jet, and have 2 washers on needle

I have a voodoo exhaust and ryca cone filtet

Go for a good ride
Block up under the sidestand so it's as close to vertical as possible and not risk falling
Drop the idle down
Then adjust