http://journal-neo.org/2016/09/06/darning-emails-against-monsanto-bayer/Perhaps most astonishing was the fact that the Seralini study was the first long-term study of the effects of a GMO diet in the world after almost two decades of widespread proliferation of GMO crops. No one else until then had made tests over the entire two year life span of rats—no government, no university, no food end-user like Nestle, Unilever, Kellogg or Kraft Foods or any such mega food concerns using GMO in their products. All previous studies were merely a brief three months or less, far too short a time to determine the possible effects of a GMO diet, as Seralini’s study dramatically confirmed.
Seralini’s group based their experiment on the same protocol as the original Monsanto study but, critically, testing more parameters more frequently. And the rats were studied for much longer—their full two year average life-time instead of just 90 days in the Monsanto study. The long time span proved critical. The first tumors only appeared after 4 to7 months into the study. In industry’s earlier 90-day study on the same GMO maize, Monsanto NK603, signs of toxicity were seen but were dismissed as “not biologically meaningful” by industry and EFSA alike. As Seralini’s study confirmed, they were indeed very biologically meaningful.
The Seralini study concluded, “In females, all treated groups died 2–3 times more than controls, and more rapidly. This difference was visible in 3 male groups fed GMOs. All results were hormone and sex dependent, and the pathological profiles were comparable. Females developed large mammary tumors almost always more often than and before controls; the pituitary was the second most disabled organ; the sex hormonal balance was modified by GMO and Roundup treatments. In treated males, liver congestions and necrosis were 2.5–5.5 times higher. This pathology was confirmed by optic and transmission electron microscopy. Marked and severe kidney nephropathies were also generally 1.3–2.3 greater. Males presented 4 times more large palpable tumors than controls…”
Four times means four hundred percent more large tumors in GMO fed rats than in normally fed ones of the control group. Moreover, the Seralini study reported, “By the beginning of the 24th month, 50–80% of female animals had developed tumors in all treated groups, with up to 3 tumors per animal, whereas only 30% of controls [non-GMO-fed—w.e.] were affected. The Roundup treatment groups showed the greatest rates of tumor incidence with 80% of animals affected with up to 3 tumors for one female, in each group.”
Seralini’s 2012 study also independently confirmed carcinogenic effects of Monsanto’s Roundup herbicide paired with the GMO corn. Roundup is a glyphosate-based weed-killer, the world’s most widely-used one that has just been recertified for 18 months by the EU Commission, despite unprecedented calls for its ban.
The Seralini study stated, “We observed a strikingly marked induction of mammary tumors by R (Roundup) alone, a major formulated pesticide, even at the very lowest dose administered. R has been shown to disrupt aromatase which synthesizes estrogens (Richard et al., 2005), but to also interfere with estrogen and androgen receptors in cells (Gasnier et al., 2009). In addition, R appears to be a sex endocrine disruptor in vivo, also in males (Romano et al., 2010). Sex steroids are also modified in treated rats. These hormone-dependent phenomena are confirmed by enhanced pituitary dysfunction in treated females.”
Mammary tumors that developed in rats fed GMO corn and/or low levels of Roundup. From the Seralini paper “Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize,” published in Food and Chemical Toxicology.
Within hours of the publication of the Seralini study in the Food and Chemical Toxicology journal, a coordinated global media campaign to discredit the conclusions was launched. No facts were presented, merely allegations that the study was “unscientific.”
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