Removed and cleaned the carb today, she needed it badly as the owner i bought her from let her sit for almost two years.  After putting the carb back together and back in the bike, I went to start her up, and she sounded weaker in the exhaust than normal (drag pipe).  

When I went to ride her, the pick up she used to have right out of first is gone.  She accelerates, but has no pickup whatsoever, it's a slow and super lagging response, even with the throttle pulled all the way back.

Any ideas?

The diaphragm lip was definitely in the slot.  What do you think is going on with the slide that would cause that?